Stanford Abdominal Transplantation

2018: Stanford Abdominal Transplant Breaks All Records!!!

***The Pediatric Transplant Program at Stanford Children’s is the number one program in volume in the nation again for 2017.  This was a milestone year for the programs. 


***The Kidney transplant program worked non-stop doing 55 transplants for an all-time high and doubling their volume.


***Heart transplant did it’s 400th heart transplant which included a technically challenging combined heart-liver transplant highlighting the strong collaboration and partnership across the organ programs.


***January 6th marked the 50th anniversary of the first adult heart transplant done by Dr. Shumway here at Stanford.


***Liver transplant launched a Regional Liver Tumor Program including a monthly multi-disciplinary teleconference to remotely facilitate discussion with physicians across the country to collaborate on the most complicated and highest risk liver tumor cases.

 

No other team has this level of expertise combining so many different specialties all working together!!!

 

Announcements

Seed Grants Funded to our very own Drs. Melcher and Martinez!

Please congratulate

Dr. Marc L. Melcher whose project is on
“Using AI to Detect Histopathologic Features Predictive of Transplantable Donor Livers”

&
Dr. Olivia M. Martinez whose project is on
“Defining the B Cell Immune Repertoire in Transplantation”

for their achievement in being funded by Stanford’s Department of Surgery’s first Seed Grant Program!  They each have been awarded $50,000!

 


November 5, 2018

Six Surgeon Scientists have been awarded funds as part of the Department of Surgery’s new Seed Grant Program. Drs. Dan Azagury (General Surgery), Paige Fox (Plastic & Reconstructive Surgery), Jason Lee (Vascular Surgery), Olivia Martinez (Abdominal Transplantation), Marc Melcher (General Surgery), and Claudia Mueller (Pediatric Surgery) were each given between $10,000 and $50,000 to fund their research for the next 12 months.

"The quality of the abstracts submitted was outstanding," said Vice Chair of Basic and Translation Research Dr. Geoffrey Gurtner. "We had 33 submissions and probably 20-25 of them were worthy of funding. We are very disappointed that we could not fund more."

The projects being funded are: 

• Bariatric Surgery vs. Catheter Ablation for the Treatment of Atrial Fibrillation (Azagury)
• Topical Antibiotic Elution in a Collagen Rich Hydrogel for Healing of Infected Wounds (Fox)
• Use of Remote Renal Ischemic Preconditioning to Reduce Incidence of Acute Kidney Injury During Complex EVAR of Juxtarenal Aortic Aneurysms (J. Lee)
• Defining the B Cell Immune Repertoire in Transplantation (Martinez)
• Using AI to Detect Histopathologic Features Predictive of Transplantable Donor Livers (Melcher)
• The effect of health mindset on perioperative anxiety and outcomes in pediatric surgery (Mueller)

"We are grateful to the inaugural Department of Surgery seed grant funding mechanism,” said Dr. Lee. Vascular Surgery resident Dr. Ken Tran (PGY-1) and Visiting Postdoctoral Scholar Dr. Celine Deslarzes-Dubuis are also working on the project. “We hope this will allow our group to further characterize renal function decline after complex endovascular aneurysm repair and potentially make an impact on improving patient outcomes with a relatively simple preoperative conditioning exercise that could be applied broadly to vascular patients."

The Seed Grant Program was born out of the Research Retreat held in May. Each proposal was reviewed by the Research Oversight Committee and scored based on significance, innovation, approach, and expected outcomes.

"We created the Stanford Surgery Seed Grant Program to correct a common 'chicken and egg' problem, namely that one cannot be competitive for large federal grants without preliminary data, but it is impossible to obtain preliminary data without resources to obtain it," said Gurtner.

Learn about their projects: http://ow.ly/psUO30mvqPx

A 6-month-old baby shouldn’t be fighting for his life. He shouldn’t have to be hurriedly baptized in a hospital room in advance of an emergency liver transplant. His young parents shouldn’t be stricken by grief and guilt during what should be a glorious period in their lives.

But this is where the Hernandez family finds itself. They currently are keeping vigil more than 100 miles away from their home in Sacramento, at the Lucile Packard Children’s Hospital Stanford in Palo Alto, praying for their son to survive an extremely rare disease that can be fatal unless luck and fate intervene. [...]


Third International Workshop on Clinical Tolerance

Stephan Busque, Samuel Strober, John Scandling at the Third International Workshop on Clinical Tolerance-Sept. 8-9, 2017 sponsored by The Stanford Institute for Immunity, Transplantation and Infection.


'Liverversary': Eugene girl celebrates her liver transplant one year later

10-year-old Lily Richard of Eugene wouldn’t be alive today if it wasn’t for a liver transplant she got exactly one year ago Sunday.  Lily’s family celebrated what they called her "Liverversary" on August 6, a one-year celebration of Lily’s new liver.  What they thought was a case of the stomach flu ended up being liver failure.  Lily was immediately flown to Stanford in California to await a liver transplant.  After being put on the top of the wait list, Lily received her transplant two days later.  Now her family is celebrating Lily’s new liver and bringing awareness about organ donations to the community.


Dr. Marc L. Melcher was featured in ASTS new briefs:
Numerous kidney exchange (kidney paired donation [KPD]) registries in the United States have gradually shifted to high-frequency match-runs, raising the question of whether this harms the number of transplants. We conducted simulations using clinical data from 2 KPD registries—the Alliance for Paired Donation, which runs multihospital exchanges, and Methodist San Antonio, which runs single-center exchanges—to study how the frequency of match-runs impacts the number of transplants and the average waiting times.


Congratulations to Trinidad Cisneros on his successful Immunology Thesis Defense

“Role of NK cells and the NK cell receptor NKG2D in the recognition and killing of stem cell derived hepatocyte-like cells”


Surgery Resident Finalist in Competition

Adam Sang, M.D. is a Stanford Surgery resident doing research in the Transplant Labs.  He is the Ernest and Amelia Gallo Endowed Postdoctoral Fellow.   He was selected as a finalist for the 2017 Northern California Chapter of the American College of Surgeons Surgical Trainee Research Competition.

Robbie Turner was only 28 years old when she was diagnosed with polycystic kidney disease — a genetic disorder that causes clumps of cysts to form in the kidneys, reducing their function over time. She knew she’d need a kidney transplant one day, and for many years, Turner and her husband thought he would be her kidney donor as he’d been approved as a perfect candidate. [...]


Dr. Busque Wins Award

The Arthur L. Bloomfield Award in Recognition of Excellence in the Teaching of Clinical Medicine.  Stephan Busque was one of the faculty that received this award.


Yarl Balachandran Wins Award

Yarl Balachandran, a Postdoc fellow in transplant immunology, was selected as a 2017 ATC Award Program winner out of approximately 100 applicants.


Marc Lucia Perez Wins Award

Marc Lucia Perez, a postdoc from the Division of Abdominal Transplantation presented an abstract entitled "STRATEGY FOR ANALYSIS OF DONOR-SPECIFIC ANTIBODY REPERTOIRE: PAIRED IMMUNOGLOBULIN HEAVY AND LIGHT CHAIN ANALYSIS OF INDIVIDUAL MEMORY B CELLS" at ESOT 2017 in Barcelona. He received the Young Investigator Award for his presentation.


Chief's Message


The Division of Abdominal Transplantation’s mission is to provide the highest quality patient care for our patients, to foster translational research, and to train the best transplant surgeons for the future.  We are highly committed to improving the care of our transplant patients through innovative clinical and basic science research both in the hospital and the lab.

Clinically, we offer transplantation services at Stanford Hospital & Clinics (SHC) and Lucile Packard Children's' Hospital at Stanford (LPCH).  Leading P.I.’s at Stanford University School of Medicine spearhead our research efforts by recruiting top post-doc fellows as well as attracting new doctoral candidates to the program.

Transplantation is also an important branch of the Immunity, Transplantation and Infection Institute at Stanford University (ITI).  ITI fosters multidisciplinary research projects to investigate in much greater detail the function of the immune system in health and disease including transplantation.  To carry out this mission, the Human Immune Monitoring Center was created.

~Dr. Carlos O. Esquivel